Sailor Piece Runes Tier List – Best Rune Buffs

My tier list ranks all Sailor Piece Runes, taking their buffs into account in terms of usefulness overall in battle. Got some spare Race Rerolls in Sailor Piece? My Sailor Piece Races guide might come in handy before you spend them.

Sailor Piece Runes Tier List

Runes are an optional, but useful, item to equip in Sailor Piece. In my rankings, I’ve made sure to list their Base and Maximum buffs.

S Tier

• Inferno Rune
  • Rarity: Mythical
  • Buffs:
    • Base:
      • Deal 70% Burn DMG (scales off of your DMG stat)
        • Burn DMG lasts for 4 seconds
    • Maximum:
      • Deal 104% Burn DMG (scales off of your DMG stat)
        • Burn DMG lasts for 4 seconds
  • How to Get:
    • Rare drop from the Rune Dungeon
• Blood Rune
  • Rarity: Mythical
  • Buffs:
    • Base:
      • Deal 65% Blood DMG (scales off of your DMG stat)
        • Blood DMG lasts for 5 seconds
    • Maximum:
      • Deal 97% Blood DMG (scales off of your DMG stat)
        • Blood DMG lasts for 5 seconds
  • How to Get:
    • Rare drop from the Rune Dungeon

A Tier

• Guardian Rune
  • Rarity: Epic
  • Buffs:
    • Base:
      • Maximum HP increases by 39% (a Multiplier of 1.39x)
    • Maximum:
      • Maximum HP increases by 59% (a Multiplier of 1.59x)
  • How to Get:
    • Rare drop from the Rune Dungeon
• Wrath Rune
  • Rarity: Mythical
  • Buffs:
    • Base:
      • DMG increases by 40% (a Multiplier of 1.4x)
    • Maximum:
      • DMG increases by 59% (a Multiplier of 1.59x)
  • How to Get:
    • Rare drop from the Rune Dungeon

B Tier

• Frost Rune
  • Rarity: Legendary
  • Buffs:
    • Base:
      • Inflict enemies with Freeze for 2 seconds
      • Deal 30% Impact DMG (scales off of your DMG stat)
    • Maximum:
      • Inflict enemies with Freeze for 3 seconds
      • Deal 44% Impact DMG (scales off of your DMG stat)
  • How to Get:
    • Rare drop from the Rune Dungeon
• Destruction Rune
  • Rarity: Legendary
  • Buffs:
    • Base:
      • DMG increases by 25% (a Multiplier of 1.25x)
    • Maximum:
      • DMG increases by 37% (a Multiplier of 1.37x)
  • How to Get:
    • Rare drop from the Rune Dungeon

C Tier

• Suppression Rune
  • Rarity: Rare
  • Buffs:
    • Base:
      • DMG Reduction increases by 10%
    • Maximum:
      • DMG Reduction increases by 15%
  • How to Get:
    • Rare drop from the Rune Dungeon

D Tier

• Fortune Rune
  • Rarity: Mythical
  • Buffs:
  • How to Get:
    • Rare drop from the Rune Dungeon

How to Get Runes

The only way to get Runes in Sailor Piece is by delving into Rune Dungeons. Each NPC you defeat has a chance to drop a random Rune. Runes of a higher rarity are much less likely to appear.

How to Enter the Rune Dungeon

The Rune Dungeon can be entered by using a Dungeon Key. This Epic rarity item is obtainable via World Bosses, but not the Shadow World Boss, so keep that in mind. Take note that Dungeon Keys are not a guaranteed drop when defeating World Bosses.

The World Bosses that drop Dungeon Keys are:

• Saber
• Sukuna
  • Location: Shibuya Station
• Gojo
  • Location: Shibuya Station
• Yuji
  • Location: Shibuya Station
• Jinwoo
• Ragna
  • Location: Christmas Island (limited-time seasonal event)
• Aizen
• Qin Shi
• Alucard
• Strongest in History
  • Location: Shinjuku Island
• Strongest of Today
  • Location: Shinjuku Island
• Ichigo
• Rimuru
• Madoka
  • Location: Valentine Island (limited-time seasonal event)
• Gilgamesh

There’s also a rare chance for Dungeon Keys to appear in chests.

Beating the Rune Dungeon

The Rune Dungeon features 15 waves in total. You can choose between 4 difficulties, including Easy, Medium, Hard, and Extreme. The higher the difficulty you set, the higher the drop chance.

There are specific mobs that appear within the Rune Dungeon, which are:

• Raiders
• Commanders
• Black Knights
• Knights